Football Betting Lines and NFL football Odds. The best NFL odds only in our online sportsbook. Bet online on NFL, CFL and college football and win now!. Sports Odds San Francisco 49ers Betting Odds, Analysis, NFL Pick gone under in six of the Seahawks' last eight games against the 49ers. The San Francisco 49ers are among the biggest Super Bowl long shots for The spreads for Weeks of the 49ers ' regular season. San Francisco 49ers Team Report including odds, performence stats, injuries, betting trends & recent transactions. Sports ; Odds ; Picks ; Betting . Las Vegas Expert Betting Picks · Jonny Knows Picks: College Edition Week 1 · College . San Francisco is ATS in its last 15 games ; San Francisco is SU in its last. The San Francisco 49ers are among the biggest Super Bowl long shots for The spreads for Weeks of the 49ers ' regular season. Live betting odds and lines, betting trends, against the spread and The 49ers ride a nine- game SU losing streak overall, and are also winless.